Dynamic of a Multi-serotype Epidemic Model with Distributed Delay

Abstract

Motivated by the growing discussion about dengue fever, we proposed a model to study a multi-serotype infectious disease, for example, dengue. The main purpose is to include and analyze the effect of the general time  delay on the model describing the length of the cross immunity protection and the effect of ADE-Antibody Dependent Enhancement, both characteristic of Dengue fever [2]. As an illustration, in this work, we restrict ourselves to two serotypes.[...]